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| All Schools |
| All Sports |
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| Football | | 9.02.2022 – Freeport 35, Lisbon/St. Dominic 22 |
| 9.09.2022 – Fryeburg Academy 24, Lisbon/St. Dominic 8 |
| 9.16.2022 – Lisbon/St. Dominic 48, Oak Hill 6 |
| 9.23.2022 – Lisbon/St. Dominic 14, Foxcroft Academy 13 |
| 9.30.2022 – Lisbon/St. Dominic 20, Medomak Valley 7 |
| 10.07.2022 – York 41, Lisbon/St. Dominic 20 |
| 10.21.2022 – Lisbon/St. Dominic 24, Poland Regional 7 |
| 10.28.2022 – Lisbon/St. Dominic 36, Hall-Dale/Winthrop/Maranacook 21 |
| 11.04.2022 – Lisbon/St. Dominic 41, John Bapst/Bangor Christian 0 |
| 11.11.2022 – Lisbon/St. Dominic 28, Freeport 21 |
| 11.19.2022 – Foxcroft Academy 41, Lisbon/St. Dominic 22 |
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