| • All Games for All Schools on 9/16/2022 |
| |
| Football |
| 9.16.2022 – Lawrence 58, Bangor 6 |
| 9.16.2022 – Edward Little 22, Brewer 20 |
| 9.16.2022 – Windham 46, Brunswick 0 |
| 9.16.2022 – Skowhegan 28, Cony 0 |
| 9.16.2022 – Mount Blue 22, Deering 18 |
| 9.16.2022 – Cape Elizabeth 34, Falmouth 16 |
| 9.16.2022 – Cheverus 20, Fryeburg Academy 6 |
| 9.16.2022 – Biddeford 50, Gorham 28 |
| 9.16.2022 – Yarmouth 36, Gray-New Gloucester 14 |
| 9.16.2022 – Lake Region 38, Greely 12 |
| 9.16.2022 – Hampden Academy 035, Maine Central Institute 6 |
| 9.16.2022 – Mountain Valley 36, Maranacook 0 |
| 9.16.2022 – Scarborough 29, Marshwood 28 |
| 9.16.2022 – Gardiner 16, Messalonskee 14 |
| 9.16.2022 – Spruce Mountain 54, Morse 22 |
| 9.16.2022 – Waterville 26, Mount Desert Island 20 |
| 9.16.2022 – Kennebunk 41, Noble 7 |
| 9.16.2022 – Medomak Valley 35, Nokomis 0 |
| 9.16.2022 – Lisbon/St. Dominic 48, Oak Hill 6 |
| 9.16.2022 – Foxcroft Academy 74, Old Town 6 |
| 9.16.2022 – Oxford Hills 34, Sanford 3 |
| 9.16.2022 – Massabesic 14, South Portland 13 |
| 9.16.2022 – York 22, Westbrook 6 |
| 9.16.2022 – Hermon 36, Oceanside 30 |
| 9.16.2022 – Mattanawcook/Lee/Penobscot 40, Schenck/Stearns 30 |
| 9.16.2022 – Dexter 58, Houl/Hodg/H. Christ/S. Aroos. 44 |
| 9.16.2022 – Hall-Dale/Winthrop/Maranacook 56, Madison/Carrabec/Valley 0 |
| 9.16.2022 – Poland Regional 20, John Bapst/Bangor Christian 7 |
